Structural Analysis by Mass Spectrometry

Applications

• Determination of composition and stoichiometry of molecular complexes
• Characterization of interaction partners, thermodynamics, and kinetics
• Structural and conformational analysis using ion mobility
• Study of protein dynamics using HDX-MS

These approaches apply to systems ranging from soluble proteins to complex membrane assemblies and are particularly suited for dynamic and heterogeneous systems.

Technologies

• Hydrogen-Deuterium Exchange (HDX)
• Native Mass Spectrometry

Sites