Molecular Interaction Analysis

Description / Workflow

Characterization of multiprotein complexes associated with a specific protein or cellular function.

Applications

• Protein–protein interaction analysis
• Antibody epitope mapping
• Determination of binding affinities and kinetic constants
• Interaction validation
• Drug and antibody screening

Requirements / Constraints

• Availability of molecules in recombinant, purified, or semi-purified form

Technologies

• Surface Plasmon Resonance (SPR)
• Nano-Differential Scanning Fluorimetry (Nano-DSF)

Sites